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7 months ago - Translate - Youtube

Immune cells tackle a human obstacle course

Immune cells inside the body need to make their way through densely packed tissues, squeezing through gaps and finding the most efficient route. During metastasis, cancer cells may make use of a similar type of locomotion. Now, experiments reveal how the cells probe different paths and use their bulky nucleus to gauge the size of gaps. Read more about this research: https://www.nature.com/articles/s41586-019-1087-5 3rd April 2019

https://youtu.be/uKid8QmBI0I

FDA Approves Optimizer Implant for CRT-Ineligible Heart Failure
The US Food and Drug Administration (FDA) has approved another device therapy for patients with chronic moderate to severe heart failure, the Optimizer Smart System (Impulse Dynamics), the agency and the company announced today.

The specified indication is for improving 6-minute walk distance, quality of life, and other aspects of functional status of patients with symptomatic heart failure in sinus rhythm despite optimal medical therapy.

The indication requires that patients not qualify for cardiac resynchronization therapy (CRT), which would include those with narrow QRS intervals on electrocardiography, and to have a left ventricular ejection fraction (LVEF) of 25% to 45%.

Impulse Dynamics notes that the Optimizer system, which is already on the market in Europe, Brazil, India, and elsewhere around the world, consists of an endocardial lead array connected to a subcutaneous battery and pulse generator that resembles a standard pacemaker.

It delivers a therapy the company calls cardiac contractility modulation (CCM), consisting of pulses delivered to specific myocardial sites during the cardiac cycle's absolute refractory period.

The stimulation doesn't engage cardiac rhythm but is believed to remodel myocardial biochemistry, first near the stimulation site and more expansively over long-term use in a way that seems to eventually improve global contractile function, as previously described by theheart.org | Medscape Cardiology.

The FDA based its approval on several randomized trials, including the FIX-HF-5C study, which was published last year. Collectively in different studies, Optimizer treatment has been associated with significant improvements in LVEF, walk distance, and symptoms. Registry data have suggested it can cut heart-failure hospitalizations and prolong survival.

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11 months ago - Translate - Youtube

Supraspinatus | Muscle Anatomy

In this tutorial on the supraspinatus muscle we will go through its anatomy covering the Origin, Insertion, Action, Nerve Supply and Blood Supply. We hope you enjoy this tutorial and make sure you subscribe for more! http://www.anatomyzone.com 3D anatomy tutorial on using the BioDigital Human (http://www.biodigitalhuman.com). This video tutorial was created using images from our partners at OpenStax College, these images can be downloaded free from: http://cnx.org/contents/14fb4ad7-39a1-4eee-ab6e-3ef2482e3e22@6.11 -------------------- Join the Facebook page for updates: http://www.facebook.com/anatomyzone Follow me on twitter: http://www.twitter.com/anatomyzone Subscribe to the channel for more videos and updates: http://www.youtube.com/subscription_center?add_user=theanatomyzone

https://youtu.be/6DEtdFMTblA
11 months ago - Translate - Youtube

Biceps Brachii | Muscle Anatomy

In this tutorial on the biceps brachii muscle we will cover its; origin, insertion, action, nerve supply, blood supply and a quick clinical correlation. We hope you find this tutorial useful for your learning! http://www.anatomyzone.com 3D anatomy tutorial on using the BioDigital Human (http://www.biodigitalhuman.com). This video tutorial was created using images from our partners at OpenStax College, these images can be downloaded free from: http://cnx.org/contents/14fb4ad7-39a1-4eee-ab6e-3ef2482e3e22@6.11 -------------------- Join the Facebook page for updates: http://www.facebook.com/anatomyzone Follow me on twitter: http://www.twitter.com/anatomyzone Subscribe to the channel for more videos and updates: http://www.youtube.com/subscription_center?add_user=theanatomyzone

https://youtu.be/MWuF57uNC0M

Removal of large epidermoid cyst from floor of the mouth

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